About Us

OnLume Brings Fluorescence Image-Guided Surgery out of the Dark.

What is OnLume?

OnLume Surgical is a Madison, WI based medical device company that develops innovative imaging technology designed to advance surgical precision, optimize patient outcomes and  reduce morbidity and costs.  

We have developed a new standard in fluorescence-guided surgery (FGS) to provide surgeons with improved visualization of critical anatomy in real-time during surgery. Our novel technology provides superior image quality with low fluorescent agent concentrations. And, it is optimized for surgical workflows  –  including compatibility with ambient operating room lighting!

The OnLume Imaging System is compatible with a broad and growing spectrum of targeted fluorescent drugs for applications across a wide range of surgical specialties.

The OnLume system has been cleared by the US Food and Drug Administration (FDA) for fluorescence imaging of blood flow and tissue perfusion before, during, and after vascular, gastrointestinal, organ transplant, plastic, reconstructive, and micro surgeries. 

The use of FDA-approved indocyanine green (ICG) dye in such applications helps visualize vascular patency and identify regions of poor blood flow that may lead to post-surgical complications. Future applications of OnLume’s FGS platform include cancer margin imaging and nerve imaging.

Our Mission, Vision & Values 

At OnLume Surgical, we are driven to unleash the full clinical potential of fluorescence-guided surgery through the passionate, skillful application of science and innovation.

We love people as much as we love science, engineering, and medicine. We value life as much as we do innovation. Fueled by our values, we undertake each day the bold commercialization of our novel fluorescence-guided surgical imaging devices to advance surgical precision for the benefit of worldwide public health. 

Why is this important? Because existing fluorescence-guided surgery technology only scratches the surface of what is possible. We’re eager to show the world how our novel approach dramatically enhances surgical visualization and precision – and can improve patient outcomes. Visit our technology page for more information.

What makes OnLume uniquely prepared to achieve these monumental goals? We benefit from and are grateful for the sturdy roots we have developed in the fertile soil of the science and medical communities of the University of Wisconsin – Madison campus. Explore more here.

Now is a unique moment in time. Myriad FGS drugs are being developed by scientists worldwide. By seeking out and collaborating with the best of these scientists, institutions, and companies, we will optimize visibility of vessels, nerves and cancer margins in real time during surgery in ways heretofore thought impossible. 



Thomas “Rock” Mackie, PhD
Executive Chairman/Co-founder

Rock is a medical physicist turned serial entrepreneur, Chief Innovation Officer at the University of Wisconsin Hospital, and Emeritus Director of Medical Engineering at the Morgridge Institute for Research. Rock has a track record of commercializing inventions and is one of the co-founders of TomoTherapy ($1B IPO), acquired by Accuray, which continues to manufacture in Madison.

Carl Gulbrandsen, JD PhD
Independent Board Member

Carl is the former Managing Director of the Wisconsin Alumni Research Foundation (WARF), a worldwide leader in university technology transfer. As an expert in IP, patent litigation, and licensing, he previously served as general counsel to medical device companies including Lunar Inc. and Bone Care International Inc.

Kevin Eliceiri, PhD

Kevin Eliceiri is the RRF Walter H. Helmerich Professor of Medical Physics and Biomedical Engineering at the UW-Madison and is an internationally known expert in advanced light microscopy. He also leads multiscale imaging efforts at the UW-Madison and the Morgridge Institute for Research. Kevin has a long track record of developing advanced optical and computational techniques for cancer imaging.

Andreas Velten, PhD

Andreas is an Assistant Professor in the Department of Electrical and Computer Engineering and the Department of Biostatistics & Medical Informatics. He has extensive experience in optics and software design; he was one of “Top 35 Under 35”innovators in MIT’s Technology Review and received the Popular Mechanics Breakthrough Award in 2012.

Benjamin Titz, PhD

Ben is a research medical physicist and biomedical engineer with 10+ years of experience in translational research and oncologic molecular imaging, in particular PET and in vivo optical imaging. Ben has industry experience in business development, drug development, phase 0-2 imaging trials, as well as FDA guidance and regulations.

Adam Uselmann, PhD

Adam is a medical physicist, engineer, and entrepreneur with over 10 years of experience in medical imaging, device design and software development in both academia and industry. Adam is committed to translating medical technologies into clinical use and increasing adoption of techniques that improve patient care and outcomes.


James A. Bowman
Chief Executive Officer

Jim has spent his entire career advancing innovative life science technologies.  Jim received his Bachelor of Science degree in BioMedical Engineering from Marquette University in Milwaukee, Wisconsin.  He is also a graduate of Harvard Business School’s OPM program, focused on entrepreneurial strategy and operations.  Jim has held senior leadership positions in growing MedTech companies including as CEO, President and Director of public and private medical device companies.  Jim has driven the business development of disruptive technologies in firms such as, C.R. BARD, Ohmeda (BOC Healthcare), Surgical Laser Technologies, CloudCath, Encision and PharmaJet, where he has been focused on technologies that advance the standard of care and improve patient outcome.

Adam Uselmann, PhD

Adam is a medical physicist, engineer, and entrepreneur with over 10 years of experience in medical imaging, device design and software development in both academia and industry. Adam is committed to translating medical technologies into clinical use and increasing adoption of techniques that improve patient care and outcomes.

Ray Heller
VP of Sales & Marketing

Ray has over 30 years’ experience in domestic and international Sales & Marketing in the MedTech industry. Ray received his Bachelor of Science degree in Marketing from Northern Illinois University. He has been a Vice President for prominent medical device companies including Medtronic, ConMed, Medline and Ohio Medical.  In addition, Ray has extensive start-up experience at several healthcare organizations. 

Daniel P. Seemuth, PhD
VP of Engineering

Daniel is passionate about cooperative design, where every person and piece works together to create an integrated, complex system. He enjoys the interdisciplinary teamwork and co-design that are key to creating a product in which every component is engineered with a view of how it fits into the overall product. His diverse skill set is well-suited to his role at OnLume, where he is responsible for the imaging system architecture, electrical design, firmware, and software. He has over 15 years of experience in embedded systems, electronics design, software and firmware development, and optical lighting and imaging systems in both academic and industry settings. Daniel received his BS, MS, and PhD in Electrical Engineering from the University of Wisconsin-Madison.

Christie Lin, PhD
VP of Research

Christie is an expert in quantitative imaging with an extensive background in medical physics and engineering. She received her BS and MS in Nuclear Science and Engineering from MIT and PhD in Medical Physics from the University of Wisconsin-Madison. Christie is passionate on developing innovative imaging technology to enable data-driven decisions in surgical applications. In her free time, she is an avid knitter, an outdoor enthusiast, and the President of the MIT Club of Wisconsin.

Greg Bange
Director of RA/QA

Greg has over 30 years experience in engineering management and design with a specific focus on medical device compliance to FDA regulations. Prior to OnLume, Greg held regulatory positions at General Electric, Accuray, Tomotherapy, and Philips, having authored or led over a dozen FDA 510(k) submissions in these previous roles.

David Bunger, MS
Lead Mechanical Engineer

David is an expert mechanical engineer with extensive experience in the development and fabrication of precision optomechanical instruments. His user-centered approach to design marries optimized ergonomics with powerful functionality to create innovative tools for medical and life science professionals. David’s previous experience includes research and development at Bruker Fluorescence Microscopy, Prairie Instruments, and Trek Bicycles. David earned his BS in Mechanical Engineering from Tufts University, and an MS in Mechanical Engineering from the University of Wisconsin-Madison.